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Effects of intravesical prostaglandin E(2) on bladder function are preserved in capsaicin-desensitized rats

Prostaglandin E(2) (PGE(2)) instilled into the bladder generates symptoms of urinary urgency in healthy women and reduces bladder capacity and urethral pressure in both humans and female rats. Systemic capsaicin desensitization, which causes degeneration of C-fibers, prevented PGE(2)-mediated reduct...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Renal Physiol
Main Authors: Hokanson, James A., Langdale, Christopher L., Milliken, Philip H., Sridhar, Arun, Grill, Warren M.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948121/
https://ncbi.nlm.nih.gov/pubmed/33283648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00302.2020
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