The Effects of Ivacaftor on Bone Density and Microarchitecture in Children and Adults with Cystic Fibrosis

CONTEXT: Cystic fibrosis (CF) transmembrane conductance (CFTR) dysfunction may play a role in CF-related bone disease (CFBD). Ivacaftor is a CFTR potentiator effective in improving pulmonary and nutritional outcomes in patients with the G551D-CFTR mutation. The effects of ivacaftor on bone health ar...

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Udgivet i:J Clin Endocrinol Metab
Main Authors: Putman, Melissa S, Greenblatt, Logan B, Bruce, Michael, Joseph, Taisha, Lee, Hang, Sawicki, Gregory, Uluer, Ahmet, Sicilian, Leonard, Neuringer, Isabel, Gordon, Catherine M, Bouxsein, Mary L, Finkelstein, Joel S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Clinical Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947772/
https://ncbi.nlm.nih.gov/pubmed/33258950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgaa890
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