Therapeutic Targeting of Neutrophil Extracellular Traps Improves Primary and Secondary Intention Wound Healing in Mice

BACKGROUND: Neutrophils are the first responders in wound healing after injury that mediate pro- and anti-inflammatory activities i.a. through the formation of extracellular traps (NETs). However, excessive NETs presence in wound tissue can cause local hyperinflammation and -coagulation resulting in...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Heuer, Annika, Stiel, Carolin, Elrod, Julia, Königs, Ingo, Vincent, Deirdre, Schlegel, Patrick, Trochimiuk, Magdalena, Appl, Birgit, Reinshagen, Konrad, Raluy, Laia Pagerols, Boettcher, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947714/
https://ncbi.nlm.nih.gov/pubmed/33717100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.614347
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