Association of Survival and Immune-Related Adverse Events With Anti-PD-1/PD-L1 and Anti-CTLA-4 Inhibitors, Alone or Their Combination for the Treatment of Cancer: A Systematic Review and Meta-Analysis of 13 Clinical Trials

BACKGROUND: Cancer, with sustained high mortality, is a worldwide threat to public health. Despite the survival benefit over conventional therapies shown in immune checkpoint inhibitor (ICI), only a minority of patients benefit from single ICI. But combination therapy holds the promise of achieving...

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Vydáno v:Front Oncol
Hlavní autoři: Zhang, Leyin, Sun, Leitao, Zhou, Yiwen, Yu, Jieru, Lin, Yingying, Wasan, Harpreet S., Shen, Minhe, Ruan, Shanming
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947606/
https://ncbi.nlm.nih.gov/pubmed/33718135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.575457
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