Exon 20 YVMA insertion is associated with high incidence of brain metastasis and inferior outcome of chemotherapy in advanced non-small cell lung cancer patients with HER2 kinase domain mutations

BACKGROUND: Chemotherapy remains the standard care for HER2 mutated advanced non-small cell lung cancer (NSCLC) even though several targeted drugs showed promising results in preliminary stages. This study aimed to investigate the association of mutation variants with clinical features and the effic...

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Detalhes bibliográficos
Publicado no:Transl Lung Cancer Res
Main Authors: Yang, Shuo, Wang, Yan, Zhao, Chao, Li, Xuefei, Liu, Qian, Mao, Shiqi, Liu, Yiwei, Yu, Xiaofei, Wang, Wanying, Tian, Qinrun, Pan, Yingying, Xiong, Anwen, Chen, Bin, Gao, Guanghui, Li, Wei, He, Yayi, Wu, Fengying, Chen, Xiaoxia, Su, Chunxia, Ren, Shengxiang, Zhou, Caicun
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947396/
https://ncbi.nlm.nih.gov/pubmed/33718019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr-20-559
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