EGFR variant allele frequency predicts EGFR-TKI efficacy in lung adenocarcinoma: a multicenter study

BACKGROUND: Although lung adenocarcinoma (LADC) with sensitizing mutations of the epidermal growth factor receptor (EGFR) is highly sensitive to EGFR tyrosine kinase inhibitors (EGFR-TKIs), in most cases disease progression inevitably occurs. Our aim was to investigate the predictive and prognostic...

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Publicado no:Transl Lung Cancer Res
Main Authors: Gieszer, Balazs, Megyesfalvi, Zsolt, Dulai, Viktoria, Papay, Judit, Kovalszky, Ilona, Timar, Jozsef, Fillinger, Janos, Harko, Tunde, Pipek, Orsolya, Teglasi, Vanda, Regos, Eszter, Papp, Gergo, Szallasi, Zoltan, Laszlo, Viktoria, Renyi-Vamos, Ferenc, Galffy, Gabriella, Bodor, Csaba, Dome, Balazs, Moldvay, Judit
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947383/
https://ncbi.nlm.nih.gov/pubmed/33718012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr-20-814
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