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Epigallocatechin gallate alters leukotoxin secretion and Aggregatibacter actinomycetemcomitans virulence

OBJECTIVES: We and others have previously shown that epigallocatechin gallate (EGCg) inhibits the activity of an important virulence factor, leukotoxin (LtxA), produced by the oral bacterium Aggregatibacter actinomycetemcomitans, suggesting the potential use of this molecule as an anti-virulence str...

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Détails bibliographiques
Publié dans:J Pharm Pharmacol
Auteurs principaux: Chang, En Hyung, Brown, Angela C
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947220/
https://ncbi.nlm.nih.gov/pubmed/33793838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jpp/rgaa051
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