Mucosal Nanoemulsion Allergy Vaccine Suppresses Alarmin Expression and Induces Bystander Suppression of Reactivity to Multiple Food Allergens

We have demonstrated that intranasal immunotherapy with allergens formulated in a nanoemulsion (NE) mucosal adjuvant suppresses Th2/IgE-mediated allergic responses and protects from allergen challenge in murine food allergy models. Protection conferred by this therapy is associated with strong suppr...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Farazuddin, Mohammad, Landers, Jeffrey J., Janczak, Katarzyna W., Lindsey, Hayley K., Finkelman, Fred D., Baker, James R., O’Konek, Jessica J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946984/
https://ncbi.nlm.nih.gov/pubmed/33717078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.599296
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