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Whole-brain tissue mapping toolkit using large-scale highly multiplexed immunofluorescence imaging and deep neural networks

Mapping biological processes in brain tissues requires piecing together numerous histological observations of multiple tissue samples. We present a direct method that generates readouts for a comprehensive panel of biomarkers from serial whole-brain slices, characterizing all major brain cell types,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Maric, Dragan, Jahanipour, Jahandar, Li, Xiaoyang Rebecca, Singh, Aditi, Mobiny, Aryan, Van Nguyen, Hien, Sedlock, Andrea, Grama, Kedar, Roysam, Badrinath
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946933/
https://ncbi.nlm.nih.gov/pubmed/33692351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21735-x
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