Dysregulation of IL-17/IL-22 Effector Functions in Blood and Gut Mucosal Gamma Delta T Cells Correlates With Increase in Circulating Leaky Gut and Inflammatory Markers During cART-Treated Chronic SIV Infection in Macaques

HIV-associated inflammation has been implicated in the premature aging and increased risk of age-associated comorbidities in cART-treated individuals. However, the immune mechanisms underlying the chronic inflammatory state of cART-suppressed HIV infection remain unclear. Here, we investigated the r...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Walker, Edith M., Slisarenko, Nadia, Gerrets, Giovanni L., Grasperge, Brooke F., Mattison, Julie A., Kissinger, Patricia J., Welsh, David A., Veazey, Ronald S., Jazwinski, S. Michal, Rout, Namita
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946846/
https://ncbi.nlm.nih.gov/pubmed/33717202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.647398
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