Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma

We present a proteogenomic study of 108 human papilloma virus (HPV)-negative head and neck squamous cell carcinomas (HNSCCs). Proteomic analysis systematically catalogs HNSCC-associated proteins and phosphosites, prioritizes copy number drivers and highlights an oncogenic role for RNA processing gen...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Huang, Chen, Chen, Lijun, Savage, Sara R., Eguez, Rodrigo Vargas, Dou, Yongchao, Li, Yize, da Veiga Leprevost, Felipe, Jaehnig, Eric J., Lei, Jonathan T., Wen, Bo, Schnaubelt, Michael, Krug, Karsten, Song, Xiaoyu, Cieślik, Marcin, Chang, Hui-Yin, Wyczalkowski, Matthew A., Li, Kai, Colaprico, Antonio, Li, Qing Kay, Clark, David J., Hu, Yingwei, Cao, Liwei, Pan, Jianbo, Wang, Yuefan, Cho, Kyung-Cho, Shi, Zhiao, Liao, Yuxing, Jiang, Wen, Anurag, Meenakshi, Ji, Jiayi, Yoo, Seungyeul, Zhou, Daniel Cui, Liang, Wen-Wei, Wendl, Michael, Vats, Pankaj, Carr, Steven A., Mani, D. R., Zhang, Zhen, Qian, Jiang, Chen, Xi S., Pico, Alexander R., Wang, Pei, Chinnaiyan, Arul M., Ketchum, Karen A., Kinsinger, Christopher R., Robles, Ana I., An, Eunkyung, Hiltke, Tara, Mesri, Mehdi, Thiagarajan, Mathangi, Weaver, Alissa M., Sikora, Andrew G., Lubiński, Jan, Wierzbicka, Małgorzata, Wiznerowicz, Maciej, Satpathy, Shankha, Gillette, Michael A., Miles, George, Ellis, Matthew J., Omenn, Gilbert S., Rodriguez, Henry, Boja, Emily S., Dhanasekaran, Saravana M., Ding, Li, Nesvizhskii, Alexey I., El-Naggar, Adel K., Chan, Daniel W., Zhang, Hui, Zhang, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946781/
https://ncbi.nlm.nih.gov/pubmed/33417831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2020.12.007
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