ImmunoPET-informed sequence for focused ultrasound-targeted mCD47 blockade controls glioma

Phagocytic immunotherapies such as CD47 blockade have emerged as promising strategies for glioblastoma (GB) therapy, but the blood brain/tumor barriers (BBB/BTB) pose a persistent challenge for mCD47 delivery that can be overcome by focused ultrasound (FUS)-mediated BBB/BTB disruption. We here lever...

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Publicat a:J Control Release
Autors principals: Sheybani, Natasha D., Breza, Victoria R., Paul, Soumen, McCauley, Katelyenn S., Berr, Stuart S., Miller, G. Wilson, Neumann, Kiel D., Price, Richard J.
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946780/
https://ncbi.nlm.nih.gov/pubmed/33476735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2021.01.023
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