Secretory IgA N-glycans contribute to the protection against E. coli O55 infection of germ-free piglets

Mucosal surfaces are colonized by highly diverse commensal microbiota. Coating with secretory IgA (SIgA) promotes the survival of commensal bacteria while it inhibits the invasion by pathogens. Bacterial coating could be mediated by antigen-specific SIgA recognition, polyreactivity, and/or by the SI...

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Veröffentlicht in:Mucosal Immunol
Hauptverfasser: Raskova Kafkova, Leona, Brokesova, Diana, Krupka, Michal, Stehlikova, Zuzana, Dvorak, Jiri, Coufal, Stepan, Fajstova, Alena, Srutkova, Dagmar, Stepanova, Katerina, Hermanova, Petra, Stepankova, Renata, Uberall, Ivo, Skarda, Jozef, Novak, Zdenek, Vannucci, Luca, Tlaskalova-Hogenova, Helena, Jiraskova Zakostelska, Zuzana, Sinkora, Marek, Mestecky, Jiri, Raska, Milan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group US 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946640/
https://ncbi.nlm.nih.gov/pubmed/32973324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-020-00345-8
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