HDAC inhibition potentiates anti-tumor activity of macrophages and enhances anti-PD-L1-mediated tumor suppression

Despite the widespread use of the blockade of immune checkpoints, for a significant number of cancer patients, these therapies have proven ineffective, presumably due to the immunosuppressive nature of the tumor microenvironment (TME). Critical drivers of immune escape in the TME include tumor-assoc...

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Veröffentlicht in:Oncogene
Hauptverfasser: Li, Xiaolei, Su, Xiao, Liu, Rui, Pan, Yongsha, Fang, Jiankai, Cao, Lijuan, Feng, Chao, Shang, Qianwen, Chen, Yongjing, Shao, Changshun, Shi, Yufang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946638/
https://ncbi.nlm.nih.gov/pubmed/33564072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01636-x
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