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Development and validation of a stability indicating RP-HPLC-DAD method for the determination of bromazepam

A reliable, selective and sensitive stability-indicating RP-HPLC assay was established for the quantitation of bromazepam (BMZ) and one of the degradant and stated potential impurities; 2-(2-amino-5-bromobenzoyl) pyridine (ABP). The assay was accomplished on a C(18) column (250 mm × 4.6 mm i.d., 5 μ...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Darwish, Hany W., Ali, Nesma A., Naguib, Ibrahim A., El Ghobashy, Mohamed R., Al-Hossaini, Abdullah M., Abdelrahman, Maha M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946308/
https://ncbi.nlm.nih.gov/pubmed/33690658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0244951
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