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Engineered human meniscus’ matrix-forming phenotype is unaffected by low strain dynamic compression under hypoxic conditions

Low oxygen and mechanical loading may play roles in regulating the fibrocartilaginous phenotype of the human inner meniscus, but their combination in engineered tissues remains unstudied. Here, we investigated how continuous low oxygen (“hypoxia”) combined with dynamic compression would affect the f...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Szojka, Alexander R. A., Moore, Colleen N., Liang, Yan, Andrews, Stephen H. J., Kunze, Melanie, Mulet-Sierra, Aillette, Jomha, Nadr M., Adesida, Adetola B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946300/
https://ncbi.nlm.nih.gov/pubmed/33690647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0248292
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