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Low-dose amikacin in the treatment of Multidrug-resistant Tuberculosis (MDR-TB)

BACKGROUND: The World Health Organization recommends intravenous amikacin for the treatment of MDR-TB at a dose of 15 mg/kg. However, higher doses are associated with significant toxicity. METHODS: Patients with MDR-TB treated at our institution receive amikacin at 8–10 mg/kg, with dose adjustment b...

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Detalhes bibliográficos
Publicado no:BMC Infect Dis
Main Authors: Sabur, Natasha F., Brar, Mantaj S., Wu, Lisa, Brode, Sarah K.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7945371/
https://ncbi.nlm.nih.gov/pubmed/33691624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-021-05947-6
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