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Exosomes for mRNA delivery: a novel biotherapeutic strategy with hurdles and hope

Over the past decade, therapeutic messenger RNAs (mRNAs) have emerged as a highly promising new class of drugs for protein replacement therapies. Due to the recent developments, the incorporation of modified nucleotides in synthetic mRNAs can lead to maximizing protein expression and reducing advers...

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Podrobná bibliografie
Vydáno v:BMC Biotechnol
Hlavní autoři: Aslan, Cynthia, Kiaie, Seyed Hossein, Zolbanin, Naime Majidi, Lotfinejad, Parisa, Ramezani, Reihaneh, Kashanchi, Fatah, Jafari, Reza
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7945253/
https://ncbi.nlm.nih.gov/pubmed/33691652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-021-00683-w
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