Downregulation of lncRNA ZNF582-AS1 due to DNA hypermethylation promotes clear cell renal cell carcinoma growth and metastasis by regulating the N(6)-methyladenosine modification of MT-RNR1

BACKGROUND: Emerging evidence confirms that lncRNAs (long non-coding RNAs) are potential biomarkers that play vital roles in tumors. ZNF582-AS1 is a novel lncRNA that serves as a potential prognostic marker of cancers. However, the specific clinical significance and molecular mechanism of ZNF582-AS1...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Yang, Wuping, Zhang, Kenan, Li, Lei, Xu, Yawei, Ma, Kaifang, Xie, Haibiao, Zhou, Jingcheng, Cai, Lin, Gong, Yanqing, Gong, Kan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7945252/
https://ncbi.nlm.nih.gov/pubmed/33691743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01889-8
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