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The epithelial-mesenchymal transition and the cytoskeleton in bioengineered systems

The epithelial-mesenchymal transition (EMT) is intrinsically linked to alterations of the intracellular cytoskeleton and the extracellular matrix. After EMT, cells acquire an elongated morphology with front/back polarity, which can be attributed to actin-driven protrusion formation as well as the ga...

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Publicat a:Cell Commun Signal
Autors principals: Leggett, Susan E., Hruska, Alex M., Guo, Ming, Wong, Ian Y.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7945251/
https://ncbi.nlm.nih.gov/pubmed/33691719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-021-00713-2
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