Th1 skewed immune response of whole virion inactivated SARS CoV 2 vaccine and its safety evaluation

We report the development and evaluation of safety and immunogenicity of a whole virion inactivated (WVI) SARS-CoV-2 vaccine (BBV152), adjuvanted with aluminum hydroxide gel (Algel), or TLR7/8 agonist chemisorbed Algel. We used a well-characterized SARS-CoV-2 strain and an established Vero cell plat...

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Опубликовано в: :iScience
Главные авторы: Ganneru, Brunda, Jogdand, Harsh, Daram, Vijaya Kumar, Das, Dipankar, Molugu, Narasimha Reddy, Prasad, Sai D., Kannappa, Srinivas V., Ella, Krishna M., Ravikrishnan, Rajaram, Awasthi, Amit, Jose, Jomy, Rao, Panduranga, Kumar, Deepak, Ella, Raches, Abraham, Priya, Yadav, Pragya D., Sapkal, Gajanan N., Shete-Aich, Anita, Desphande, Gururaj, Mohandas, Sreelekshmy, Basu, Atanu, Gupta, Nivedita, Vadrevu, Krishna Mohan
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2021
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944858/
https://ncbi.nlm.nih.gov/pubmed/33723528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102298
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