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Th1 skewed immune response of whole virion inactivated SARS CoV 2 vaccine and its safety evaluation

We report the development and evaluation of safety and immunogenicity of a whole virion inactivated (WVI) SARS-CoV-2 vaccine (BBV152), adjuvanted with aluminum hydroxide gel (Algel), or TLR7/8 agonist chemisorbed Algel. We used a well-characterized SARS-CoV-2 strain and an established Vero cell plat...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Ganneru, Brunda, Jogdand, Harsh, Daram, Vijaya Kumar, Das, Dipankar, Molugu, Narasimha Reddy, Prasad, Sai D., Kannappa, Srinivas V., Ella, Krishna M., Ravikrishnan, Rajaram, Awasthi, Amit, Jose, Jomy, Rao, Panduranga, Kumar, Deepak, Ella, Raches, Abraham, Priya, Yadav, Pragya D., Sapkal, Gajanan N., Shete-Aich, Anita, Desphande, Gururaj, Mohandas, Sreelekshmy, Basu, Atanu, Gupta, Nivedita, Vadrevu, Krishna Mohan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944858/
https://ncbi.nlm.nih.gov/pubmed/33723528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102298
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