Silencing of peroxiredoxin 1 expression ameliorates ulcerative colitis in a rat model

BACKGROUND: Peroxiredoxin 1 (PRDX1), a protein with anti-inflammatory and anti-apoptotic properties, shows elevated expression in ulcerative colitis (UC). However, PRDX1's specific role in UC is poorly understood. METHODS: UC was induced in rats using dextran sulfate sodium (DSS). In vivo RNA i...

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Bibliografiske detaljer
Udgivet i:J Int Med Res
Main Authors: Wu, Na, Du, Xinchong, Peng, Zhao, Zhang, Zetian, Cui, Lijun, Li, Duo, Wang, Rui, Ma, Maoyuan
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2021
Fag:
Pre-Clinical Research Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944532/
https://ncbi.nlm.nih.gov/pubmed/33682513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060520986313
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