Specific Cytotoxic Effect of an Auristatin Nanoconjugate Towards CXCR4(+) Diffuse Large B-Cell Lymphoma Cells

BACKGROUND AND PURPOSE: Around 40–50% of diffuse large-B cell lymphoma (DLBCL) patients suffer from refractory disease or relapse after R-CHOP first-line treatment. Many ongoing clinical trials for DLBCL patients involve microtubule targeting agents (MTAs), however, their anticancer activity is limi...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Falgàs, Aïda, Pallarès, Victor, Unzueta, Ugutz, Núñez, Yáiza, Sierra, Jorge, Gallardo, Alberto, Alba-Castellón, Lorena, Mangues, Maria Antonia, Álamo, Patricia, Villaverde, Antonio, Vázquez, Esther, Mangues, Ramon, Casanova, Isolda
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2021
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944372/
https://ncbi.nlm.nih.gov/pubmed/33716502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S289733
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