Assessing the impact of PCSK9 inhibition on coronary plaque phenotype with optical coherence tomography: rationale and design of the randomized, placebo-controlled HUYGENS study

BACKGROUND: Technological advances in arterial wall imaging permit the opportunity to visualize coronary atherosclerotic plaque with sufficient resolution to characterize both its burden and compositional phenotype. These modalities have been used extensively in clinical trials to evaluate the impac...

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Bibliografski detalji
Izdano u:Cardiovasc Diagn Ther
Glavni autori: Nicholls, Stephen J., Nissen, Steven E., Prati, Francesco, Windecker, Stephan, Kataoka, Yu, Puri, Rishi, Hucko, Thomas, Kassahun, Helina, Liao, Jason, Somaratne, Ransi, Butters, Julie, Di Giovanni, Giuseppe, Jones, Stephen, Psaltis, Peter J.
Format: Artigo
Jezik:Inglês
Izdano: AME Publishing Company 2021
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944215/
https://ncbi.nlm.nih.gov/pubmed/33708484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/cdt-20-684
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