Assessing the impact of PCSK9 inhibition on coronary plaque phenotype with optical coherence tomography: rationale and design of the randomized, placebo-controlled HUYGENS study

BACKGROUND: Technological advances in arterial wall imaging permit the opportunity to visualize coronary atherosclerotic plaque with sufficient resolution to characterize both its burden and compositional phenotype. These modalities have been used extensively in clinical trials to evaluate the impac...

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Detalhes bibliográficos
Publicado no:Cardiovasc Diagn Ther
Main Authors: Nicholls, Stephen J., Nissen, Steven E., Prati, Francesco, Windecker, Stephan, Kataoka, Yu, Puri, Rishi, Hucko, Thomas, Kassahun, Helina, Liao, Jason, Somaratne, Ransi, Butters, Julie, Di Giovanni, Giuseppe, Jones, Stephen, Psaltis, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944215/
https://ncbi.nlm.nih.gov/pubmed/33708484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/cdt-20-684
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