Diabetes Attenuates the Contribution of Endogenous Nitric Oxide but Not Nitroxyl to Endothelium Dependent Relaxation of Rat Carotid Arteries

Endothelial dysfunction is a major risk factor for several of the vascular complications of diabetes, including ischemic stroke. Nitroxyl (HNO), the one electron reduced and protonated form of nitric oxide (NO•), is resistant to scavenging by superoxide, but the role of HNO in diabetes mellitus asso...

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Vydáno v:Front Pharmacol
Hlavní autoři: Li, Jasmin Chendi, Velagic, Anida, Qin, Cheng Xue, Li, Mandy, Leo, Chen Huei, Kemp-Harper, Barbara K., Ritchie, Rebecca H., Woodman, Owen L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944142/
https://ncbi.nlm.nih.gov/pubmed/33716721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.585740
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