Loss of Quaking RNA binding protein disrupts the expression of genes associated with astrocyte maturation in mouse brain

Quaking RNA binding protein (QKI) is essential for oligodendrocyte development as myelination requires myelin basic protein mRNA regulation and localization by the cytoplasmic isoforms (e.g., QKI-6). QKI-6 is also highly expressed in astrocytes, which were recently demonstrated to have regulated mRN...

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Publicado no:Nat Commun
Main Authors: Sakers, Kristina, Liu, Yating, Llaci, Lorida, Lee, Scott M., Vasek, Michael J., Rieger, Michael A., Brophy, Sean, Tycksen, Eric, Lewis, Renate, Maloney, Susan E., Dougherty, Joseph D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7943582/
https://ncbi.nlm.nih.gov/pubmed/33750804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21703-5
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