Pre-existing Immunity to Japanese Encephalitis Virus Alters CD4 T Cell Responses to Zika Virus Inactivated Vaccine

The epidemic spread of Zika virus (ZIKV), associated with devastating neurologic syndromes, has driven the development of multiple ZIKV vaccines candidates. An effective vaccine should induce ZIKV-specific T cell responses, which are shown to improve the establishment of humoral immunity and contrib...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Lima, Noemia S., Moon, Damee, Darko, Samuel, De La Barrera, Rafael A., Lin, Leyi, Koren, Michael A., Jarman, Richard G., Eckels, Kenneth H., Thomas, Stephen J., Michael, Nelson L., Modjarrad, Kayvon, Douek, Daniel C., Trautmann, Lydie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7943459/
https://ncbi.nlm.nih.gov/pubmed/33717194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.640190
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