Emetine suppresses SARS-CoV-2 replication by inhibiting interaction of viral mRNA with eIF4E

Emetine is a FDA-approved drug for the treatment of amebiasis. Previously we demonstrated the antiviral efficacy of emetine against some RNA and DNA viruses. In this study, we evaluated the in vitro antiviral efficacy of emetine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) an...

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Bibliographische Detailangaben
Veröffentlicht in:Antiviral Res
Hauptverfasser: Kumar, Ram, Afsar, Mohammad, Khandelwal, Nitin, Chander, Yogesh, Riyesh, Thachamvally, Dedar, Ramesh Kumar, Gulati, Baldev R., Pal, Yash, Barua, Sanjay, Tripathi, Bhupendra N., Hussain, Tanweer, Kumar, Naveen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier B.V. 2021
Schlagworte:
Short Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7943376/
https://ncbi.nlm.nih.gov/pubmed/33711336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2021.105056
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