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Polygenic Risk Scores Augment Stroke Subtyping

OBJECTIVE: To determine whether the polygenic risk score (PRS) derived from MEGASTROKE is associated with ischemic stroke (IS) and its subtypes in an independent tertiary health care system and to identify the PRS derived from gene sets of known biological pathways associated with IS. METHODS: Contr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neurol Genet
Hauptverfasser: Li, Jiang, Chaudhary, Durgesh P., Khan, Ayesha, Griessenauer, Christoph, Carey, David J., Zand, Ramin, Abedi, Vida
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7943221/
https://ncbi.nlm.nih.gov/pubmed/33709033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000560
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