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Real-time monitoring of peptidoglycan synthesis by membrane-reconstituted penicillin-binding proteins
Peptidoglycan is an essential component of the bacterial cell envelope that surrounds the cytoplasmic membrane to protect the cell from osmotic lysis. Important antibiotics such as β-lactams and glycopeptides target peptidoglycan biosynthesis. Class A penicillin-binding proteins (PBPs) are bifunctio...
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| Veröffentlicht in: | eLife |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7943195/ https://ncbi.nlm.nih.gov/pubmed/33625355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61525 |
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