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Targeting the IDO-BCL2A1-Cytochrome c Pathway Promotes Apoptosis in Oral Squamous Cell Carcinoma

PURPOSE: Indolamine 2,3-dioxygenase (IDO) is the rate limiting enzyme of tryptophan degradation and is a negative prognostic factor in oral squamous cell carcinoma (OSCC) patients, while the underlying molecular mechanism remains unclear. This research aimed to explore the IDO expression and its bio...

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Publicado en:Onco Targets Ther
Main Authors: Zheng, Qiaoping, Gan, Guifang, Gao, Xianfu, Luo, Qingqiong, Chen, Fuxiang
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7942955/
https://ncbi.nlm.nih.gov/pubmed/33707952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S288692
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