Effect of acetyl-L-carnitine on hypersensitivity in acute recurrent caerulein-induced pancreatitis and microglial activation along the brain’s pain circuitry

BACKGROUND: Acute pancreatitis (AP) and recurring AP are serious health care problems causing excruciating pain and potentially lethal outcomes due to sepsis. The validated caerulein- (CAE) induced mouse model of acute/recurring AP produces secondary persistent hypersensitivity and anxiety-like beha...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: McIlwrath, Sabrina L, Starr, Marlene E, High, Abigail E, Saito, Hiroshi, Westlund, Karin N
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2021
Assuntos:
Basic Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941858/
https://ncbi.nlm.nih.gov/pubmed/33727771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v27.i9.794
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