Prolonged activation of cytomegalovirus early gene e1-promoter exclusively in neurons during infection of the developing cerebrum

The brain is the major target of congenital cytomegalovirus (CMV) infection. It is possible that neuron disorder in the developing brain is a critical factor in the development of neuropsychiatric diseases in later life. Previous studies using mouse model of murine CMV (MCMV) infection demonstrated...

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Veröffentlicht in:Acta Neuropathol Commun
Hauptverfasser: Kosugi, Isao, Arai, Yoshifumi, Baba, Satoshi, Kawasaki, Hideya, Iwashita, Toshihide, Tsutsui, Yoshihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941713/
https://ncbi.nlm.nih.gov/pubmed/33750455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01139-0
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