Evaluation of PCR‐HRM, RFLP, and direct sequencing as simple and cost‐effective methods to detect common EGFR mutations in plasma cell–free DNA of non–small cell lung cancer patients

BACKGROUND: Lung cancer patients with mutations in epidermal growth factor receptor (EGFR) gene are treated with tyrosine kinase inhibitor (TKI). AIMS: We aimed to evaluate polymerase chain reaction (PCR)–high‐resolution melting (HRM), restriction fragment length polymorphism (RFLP), and direct sequ...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Rep (Hoboken)
Auteurs principaux: Zaini, Jamal, Syahruddin, Elisna, Yunus, Muhammad, Andarini, Sita Laksmi, Hudoyo, Achmad, Masykura, Najmiatul, Yasril, Refniwita, Ridwanuloh, Asep, Hidajat, Heriawaty, Nurwidya, Fariz, Suharsono, Sony, Utomo, Ahmad R.H.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941558/
https://ncbi.nlm.nih.gov/pubmed/32721094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cnr2.1159
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