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CRISPR/Cas9‐mediated double knockout of SRPK1 and SRPK2 in a nasopharyngeal carcinoma cell line

BACKGROUND: Serine‐arginine protein kinase (SRPK) is a regulator of alternative splicing events via phosphorylation of splicing factor proteins. Oncogenic roles of SRPK1 and SRPK2 have been reported in various types of cancer. To date, only SRPK1/2 specific inhibitors and small interfering RNA (siRN...

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Detalhes bibliográficos
Publicado no:Cancer Rep (Hoboken)
Main Authors: Prattapong, Pongphol, Ngernsombat, Chawalit, Aimjongjun, Sathid, Janvilisri, Tavan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941449/
https://ncbi.nlm.nih.gov/pubmed/32671994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cnr2.1224
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