Association of Intensive vs Standard Blood Pressure Control With Magnetic Resonance Imaging Biomarkers of Alzheimer Disease: Secondary Analysis of the SPRINT MIND Randomized Trial

IMPORTANCE: Meta-analyses of randomized clinical trials have indicated that improved hypertension control reduces the risk for cognitive impairment and dementia. However, it is unclear to what extent pathways reflective of Alzheimer disease (AD) pathology are affected by hypertension control. OBJECT...

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Vydáno v:JAMA Neurol
Hlavní autoři: Nasrallah, Ilya M., Gaussoin, Sarah A., Pomponio, Raymond, Dolui, Sudipto, Erus, Guray, Wright, Clinton B., Launer, Lenore J., Detre, John A., Wolk, David A., Davatzikos, Christos, Williamson, Jeff D., Pajewski, Nicholas M., Bryan, R. Nick
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2021
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941253/
https://ncbi.nlm.nih.gov/pubmed/33683313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2021.0178
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