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Nbs1‐mediated DNA damage repair pathway regulates haematopoietic stem cell development and embryonic haematopoiesis

OBJECTIVES: DNA damages pose threats to haematopoietic stem cells (HSC) maintenance and haematopoietic system homeostasis. Quiescent HSCs in adult mouse bone marrow are resistant to DNA damage, while human umbilical cord blood‐derived proliferative HSCs are prone to cell death upon ionizing radiatio...

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Bibliografiska uppgifter
I publikationen:Cell Prolif
Huvudupphovsmän: Chen, Yu, Sun, Jie, Ju, Zhenyu, Wang, Zhao‐Qi, Li, Tangliang
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941224/
https://ncbi.nlm.nih.gov/pubmed/33586242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12972
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