Irbesartan inhibits metastasis by interrupting the adherence of tumor cell to endothelial cell induced by angiotensin II in hepatocellular carcinoma

BACKGROUND: The use of angiotensin II inhibitors is associated with a low risk of recurrence and metastasis in hepatocellular carcinoma (HCC) patients. Vascular cell adhesion molecule-1 (VCAM-1) is a key factor in tumor metastasis. METHODS: The effects of angiotensin II and irbesartan (an angiotensi...

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Detalles Bibliográficos
Publicado en:Ann Transl Med
Main Authors: Feng, Long-Hai, Sun, Hui-Chuan, Zhu, Xiao-Dong, Zhang, Shi-Zhe, Li, Xiao-Long, Li, Kang-Shuai, Liu, Xue-Feng, Lei, Ming, Li, Yan, Tang, Zhao-You
Formato: Artigo
Idioma:Inglês
Publicado: AME Publishing Company 2021
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940954/
https://ncbi.nlm.nih.gov/pubmed/33708834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-5293
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