Treatment of Chronic Venous Ulcers With Heterologous Fibrin Sealant: A Phase I/II Clinical Trial

BACKGROUND: Heterologous fibrin sealant (HFS) consists of a fibrinogen-rich cryoprecipitate extracted from Bubalus bubalis buffalo blood and a thrombin-like enzyme purified from Crotalus durissus terrificus snake venom. This study evaluated the safety and immunogenicity of HFS, estimated the best do...

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Publicado en:Front Immunol
Autores principales: Abbade, Luciana P. F., Barraviera, Silvia Regina Catharino Sartori, Silvares, Maria Regina Cavariani, Lima, Ana Beatriz B. de C. O., Haddad, Gabriela R., Gatti, Márcia A. N., Medolago, Natália Bronzatto, Rigotto Carneiro, Márcia Tonin, dos Santos, Lucilene Delazari, Ferreira, Rui Seabra, Barraviera, Benedito
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940668/
https://ncbi.nlm.nih.gov/pubmed/33708219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.627541
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