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Serotonin deficiency induced after brain maturation rescues consequences of early life adversity

Brain serotonin (5-HT) system dysfunction is implicated in depressive disorders and acute depletion of 5-HT precursor tryptophan has frequently been used to model the influence of 5-HT deficiency on emotion regulation. Tamoxifen (TAM)-induced Cre/loxP-mediated inactivation of the tryptophan hydroxyl...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Aboagye, B., Weber, T., Merdian, H. L., Bartsch, D., Lesch, K. P., Waider, J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940624/
https://ncbi.nlm.nih.gov/pubmed/33686115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83592-4
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