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Emulating randomized clinical trials with nonrandomized real-world evidence studies: First results from the RCT DUPLICATE initiative

BACKGROUND: Regulators are evaluating the use of non-interventional real-world evidence (RWE) studies to assess the effectiveness of medical products. The RCT-DUPLICATE initiative uses a structured process to design RWE studies emulating randomized controlled trials (RCTs) and compare results. Here,...

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Bibliographische Detailangaben
Veröffentlicht in:Circulation
Hauptverfasser: Franklin, Jessica M., Patorno, Elisabetta, Desai, Rishi J., Glynn, Robert J., Martin, David, Quinto, Kenneth, Pawar, Ajinkya, Bessette, Lily G., Lee, Hemin, Garry, Elizabeth M., Gautam, Nileesa, Schneeweiss, Sebastian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940583/
https://ncbi.nlm.nih.gov/pubmed/33327727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.120.051718
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