MRI-based clinical-radiomics model predicts tumor response before treatment in locally advanced rectal cancer

Neoadjuvant chemo-radiotherapy (CRT) followed by total mesorectal excision (TME) represents the standard treatment for patients with locally advanced (≥ T3 or N+) rectal cancer (LARC). Approximately 15% of patients with LARC shows a complete response after CRT. The use of pre-treatment MRI as predic...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Delli Pizzi, Andrea, Chiarelli, Antonio Maria, Chiacchiaretta, Piero, d’Annibale, Martina, Croce, Pierpaolo, Rosa, Consuelo, Mastrodicasa, Domenico, Trebeschi, Stefano, Lambregts, Doenja Marina Johanna, Caposiena, Daniele, Serafini, Francesco Lorenzo, Basilico, Raffaella, Cocco, Giulio, Di Sebastiano, Pierluigi, Cinalli, Sebastiano, Ferretti, Antonio, Wise, Richard Geoffrey, Genovesi, Domenico, Beets-Tan, Regina G. H., Caulo, Massimo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940398/
https://ncbi.nlm.nih.gov/pubmed/33686147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84816-3
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