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Two decades since the fetal insulin hypothesis: what have we learned from genetics?

In 1998 the fetal insulin hypothesis proposed that lower birthweight and adult-onset type 2 diabetes are two phenotypes of the same genotype. Since then, advances in research investigating the role of genetics affecting insulin secretion and action have furthered knowledge of fetal insulin-mediated...

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Bibliographic Details
Published in:Diabetologia
Main Authors: Hughes, Alice E., Hattersley, Andrew T., Flanagan, Sarah E., Freathy, Rachel M.
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940336/
https://ncbi.nlm.nih.gov/pubmed/33569631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-021-05386-7
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