Maternal obesity during pregnancy leads to adipose tissue ER stress in mice via miR-126-mediated reduction in Lunapark

AIMS/HYPOTHESIS: Levels of the microRNA (miRNA) miR-126-3p are programmed cell-autonomously in visceral adipose tissue of adult offspring born to obese female C57BL/6J mice. The spectrum of miR-126-3p targets and thus the consequences of its dysregulation for adipocyte metabolism are unknown. Theref...

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Veröffentlicht in:Diabetologia
Hauptverfasser: de Almeida-Faria, Juliana, Duque-Guimarães, Daniella E., Ong, Thomas P., Pantaleão, Lucas C., Carpenter, Asha A., Loche, Elena, Kusinski, Laura C., Ashmore, Thomas J., Antrobus, Robin, Bushell, Martin, Fernandez-Twinn, Denise S., Ozanne, Susan E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940301/
https://ncbi.nlm.nih.gov/pubmed/33501603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-020-05357-4
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