Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology

Compelling evidence demonstrates that miR-193a-3p is a tumor suppressor microRNA in many cancer types, and its reduced expression is linked to cancer initiation and progression, metastasis, and therapy resistance. However, its mechanism of action is not consistently described between studies, and of...

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Pubblicato in:Oncotarget
Autori principali: Telford, Bryony J., Yahyanejad, Sanaz, de Gunst, Thijs, den Boer, Harm C., Vos, Rogier M., Stegink, Marieke, van den Bosch, Marion T.J., Alemdehy, Mir Farshid, van Pinxteren, Laurens A.H., Schaapveld, Roel Q.J., Janicot, Michel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2021
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939530/
https://ncbi.nlm.nih.gov/pubmed/33747358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27894
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