Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology

Compelling evidence demonstrates that miR-193a-3p is a tumor suppressor microRNA in many cancer types, and its reduced expression is linked to cancer initiation and progression, metastasis, and therapy resistance. However, its mechanism of action is not consistently described between studies, and of...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Telford, Bryony J., Yahyanejad, Sanaz, de Gunst, Thijs, den Boer, Harm C., Vos, Rogier M., Stegink, Marieke, van den Bosch, Marion T.J., Alemdehy, Mir Farshid, van Pinxteren, Laurens A.H., Schaapveld, Roel Q.J., Janicot, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939530/
https://ncbi.nlm.nih.gov/pubmed/33747358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27894
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