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Endothelial Regulation of Drug Transport in a 3D Vascularized Tumor Model

Drug discovery and efficacy in cancer treatments are limited by the inability of pre-clinical models to predict successful outcomes in humans. Limitations remain partly due to their lack of a physiologic tumor microenvironment (TME), which plays a considerable role in drug delivery and tumor respons...

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Détails bibliographiques
Publié dans:Adv Funct Mater
Auteurs principaux: Haase, Kristina, Offeddu, Giovanni S., Gillrie, Mark R., Kamm, Roger D.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939067/
https://ncbi.nlm.nih.gov/pubmed/33692661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adfm.202002444
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