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Acquisition of cancer stem cell capacities after spontaneous cell fusion

BACKGROUND: Cancer stem/Initiating cell (CS/IC) hypothesis argues that CS/ICs are responsible of tumour initiation, drug resistance, metastasis or disease relapse. Their detection in several cancers supports this concept. However, their origin is still misunderstood. Cell fusion is shown to take par...

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Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Merle, Candice, Lagarde, Pauline, Lartigue, Lydia, Chibon, Frédéric
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7938600/
https://ncbi.nlm.nih.gov/pubmed/33678155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-021-07979-2
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