Derivatization with 2-hydrazino-1-methylpyridine enhances sensitivity of analysis of 5α-dihydrotestosterone in human plasma by liquid chromatography tandem mass spectrometry

Liquid Chromatography tandem mass spectrometry (LC-MS/MS) is the gold-standard approach for androgen analysis in biological fluids, superseding immunoassays in selectivity, particularly at low concentrations. While LC-MS/MS is established for analysis of testosterone and androstenedione, 5α-dihydrot...

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Bibliografske podrobnosti
izdano v:J Chromatogr A
Main Authors: Faqehi, Abdullah MM, Denham, Scott G, Naredo, Gregorio, Cobice, Diego F, Khan, Shazia, Simpson, Joanna P, Sabil, Ghazali, Upreti, Rita, Gibb, Fraser, Homer, Natalie ZM, Andrew, Ruth
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7938423/
https://ncbi.nlm.nih.gov/pubmed/33588275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2021.461933
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