Neuronal metabotropic glutamate receptor 8 protects against neurodegeneration in CNS inflammation

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system with continuous neuronal loss. Treatment of clinical progression remains challenging due to lack of insights into inflammation-induced neurodegenerative pathways. Here, we show that an imbalance in the neuronal r...

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Vydáno v:J Exp Med
Hlavní autoři: Woo, Marcel S., Ufer, Friederike, Rothammer, Nicola, Di Liberto, Giovanni, Binkle, Lars, Haferkamp, Undine, Sonner, Jana K., Engler, Jan Broder, Hornig, Sönke, Bauer, Simone, Wagner, Ingrid, Egervari, Kristof, Raber, Jacob, Duvoisin, Robert M., Pless, Ole, Merkler, Doron, Friese, Manuel A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7938362/
https://ncbi.nlm.nih.gov/pubmed/33661276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201290
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