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In vitro complex formation of human PYRIN domain-only protein 3 prevented by self-oligomerization of ASC PYD domain

The formation of inflammasome complexes contributes inactivation of inflammatory caspases viz caspase 1, which is generally considered essential for the innate response. Three proteins constituted this inflammasome complex, such as Nod-like receptors (NLRP or AIM2), ASC possessing caspase-recruiting...

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Detalhes bibliográficos
Publicado no:Saudi J Biol Sci
Main Authors: Ahmed Bhat, Eijaz, Sajjad, Nasreena, Ahmad Tantray, Javeed, Hor, Yan-Yan, Rather, Irfan A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7938106/
https://ncbi.nlm.nih.gov/pubmed/33732046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sjbs.2020.12.049
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